Home > Anatomy, Physiology > Induced Spinal Cord Compression in Mice

Induced Spinal Cord Compression in Mice

While there have been several pro-chiropractic studies demonstrating the effects of a spinal cord compression, this is a in-lab study done on mice. I am not in favor with animal testing, however this topic is so intriguing that I couldn’t pass it up. The study was designed to essentially observe the cellular effect of a chronic spinal cord compression. To a chiropractor, it is easy to understand that spinal cord compression could be caused by a misaligned vertebra, but in this study they used a artificial calcified mass that  continued to grow as the mice matured. The damaged that was caused by the compression was measured by the tissue response. You might want to catch up on your histology before reading the original.

It is also a nice coincidence that the location they decided to compress the spinal cord was at the C1-C2 region. We should all understand that the body has an intelligence that governs every function. Our body responds to the stresses it receives and compensates accordingly. For the most part, our body processes the stress and regains homeostasis. When there is a compressive force interfering with the communication in our body, it starts to break down. This may include a decreased cellular function or hypersensitivity to stress. As the compression continues to exist, the rest of the body begins to suffer from the decreased communication and compensations occur in various regions. The article demonstrates this breakdown in scientific terms and at the site of compression on a cellular level.

Cervical compressive myelopathy, e.g. due to spondylosis or ossification of the posterior longitudinal ligament is a common cause of spinal cord dysfunction. Although human pathological studies have reported neuronal loss and demyelination in the chronically compressed spinal cord, little is known about the mechanisms involved. In particular, the neuroinflammatory processes that are thought to underlie the condition are poorly understood.

I would certainly add “subluxation” to this list of common obstructions to the spinal cord. As for a correction of this compressive force, the article recommended “The only treatment available at present is the surgical removal of the cause of chronic spinal cord compression.” I agree, in part. Remove the interference and restore proper communication and function to the brain and body. In the case of a large calcified mass compressing on the cord, you might need the extreme option. It is much more likely that a misaligned bone may be causing the compression and can be removed by a skilled upper cervical doctor.

If this interest you, read the article. This study was not written by or for chiropractors, however the findings are relevant to chiropractic principles that every effect has an cause, that there can exist an interference caused by subluxation (compression on spinal cord by misaligned vertebrae), and this will cause dis-ease within the body.

Read full article headache


  1. 27 August 2014 at 12:54
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